Ace the Neonatal & Pediatric Respiratory Care Exam 2026 – Breathe Easy and Succeed!

Titrate FiO2 to keep SpO2 in a narrow, safe range. For neonates on mechanical ventilation, aiming for about 90–92% SpO2 provides enough oxygen delivery while reducing the risks of oxygen toxicity, such as retinopathy of prematurity and bronchopulmonary dysplasia that come with higher oxygen levels. Use continuous pulse oximetry to guide FiO2: if SpO2 falls below 90%, increase FiO2 in small steps; if SpO2 rises above 92%, decrease FiO2 gradually. This balance helps maintain adequate tissue oxygenation without exposing the infant to unnecessary hyperoxia.